In cases of severe hair loss, limited success has been achieved by using the corticosteroids clobetasol or fluocinonide , corticosteroid injections, or cream. The cream is not as effective and it takes longer in order to see results. Steroid injections are commonly used in sites where the areas of hair loss on the head are small or especially where eyebrow hair has been lost. Whether they are effective is uncertain. Some other medications that have been used are minoxidil , Elocon (mometasone) ointment (steroid cream), irritants (anthralin or topical coal tar), and topical immunotherapy ciclosporin , sometimes in different combinations. Topical corticosteroids frequently fail to enter the skin deeply enough to affect the hair bulbs, which are the treatment target,  and small lesions typically also regrow spontaneously. Oral corticosteroids decrease the hair loss, but only for the period during which they are taken, and these drugs can cause serious side effects . 
Multiple vitamins, including biotin, have been promoted for hair growth, but solid scientific studies for many of these claims are lacking. While taking biotin and other supplements marketed for hair, skin, and nails probably won't worsen anything, it may also not necessarily help the situation. Therefore, advertised hair-regrowth supplements should be approached with mild caution. There is only anecdotal evidence that oral or topical application garlic , onion juice, saw palmetto, coconut oil, evening primrose oil , apple cider vinegar, creatine, and pumpkin seed oil are of benefit for hair loss.
Low level laser therapy (LLLT) is a noninvasive treatment where red light or near-infrared light is applied with the intent of altering cell and tissue function. LLLT has been used to treat a variety of medical disorders, including osteoarthritis , carpal tunnel syndrome , tuberculosis, ulcers, Bell's palsy, neck pain, Parkinson's disease , and hair loss. The efficacy of LLLT for certain applications is controversial; however, an LLLT device was approved by the . Food and Drug Administration (FDA) in 2007 for the treatment of male pattern hair loss.