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1 through 12 years:
15 kg or less: 30 mg orally once a day
through 23 kg: 45 mg orally once a day
through 40 kg: 60 mg orally once a day
kg or greater: 75 mg orally once a day
13 years or older: 75 mg orally once a day
Duration of therapy:
-After close contact with an infected individual: 10 days
-During a community outbreak of influenza: May be continued for up to 6 weeks
-Therapy should begin within 48 hours of exposure.
-The FDA has not approved dosing for patients less than 1 year of age.
(Not approved by FDA)
AAP recommendations for full-term infants:
Less than 3 months: Not recommended unless situation judged critical.
3 months to less than 1 year: 3 mg/kg orally once a day
Assembly language programmers must be aware of hidden side effects — instructions that modify parts of the processor state which are not mentioned in the instruction's mnemonic. A classic example of a hidden side effect is an arithmetic instruction that implicitly modifies condition codes (a hidden side effect) while it explicitly modifies a register (the overt effect). One potential drawback of an instruction set with hidden side effects is that, if many instructions have side effects on a single piece of state, like condition codes, then the logic required to update that state sequentially may become a performance bottleneck. The problem is particularly acute on some processors designed with pipelining (since 1990) or with out-of-order execution . Such a processor may require additional control circuitry to detect hidden side effects and stall the pipeline if the next instruction depends on the results of those effects.