Low dose steroids for ra

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a) Amiodarone

This is a powerful drug for the control of atrial and ventricular arrhythmias.

The dosage regime is as follows (via a central line):-

300 mgs in 100mls 5 % Dextrose over 1 hour
then 900 mgs in 250 mls 5% Dextrose over 23 hours

The initial oral dose is then 200 mgs tds for 1 week reduced thereafter to bd followed by maintenance od.

( Note. Some has a preference not to use this agent first line and prefers Digoxin)

b) Cardioversion

A DC shock applied to the chest is an effective way of restoring sinus rhythm, particularly supraventricular tachycardia. This is usually carried out by the Cardiologist.

3. Ventricular Arrhythmias

VF\VT - See cardiac arrest

mg/m2 PO/IM daily for 4 to 6 weeks or until remission occurs; followed by twice weekly maintenance therapy with a total weekly dose of 30 mg/m2 PO/IM. Children receiving doses of 20 to 30 mg/m2/week ( to 1 mg/kg/week) may have better absorption and fewer GI side effects if methotrexate is administered either IM or subcutaneous. Several different combination chemotherapy regimens have been used for both induction and maintenance therapy in acute lymphoblastic leukemia. The prescriber should be familiar with new advances in antileukemic therapy.

Low dose steroids for ra

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